Personalized mRNA vaccines in glioblastoma therapy: from rational design to clinical trials

Abstract Glioblastomas (GBMs) are the most common and aggressive malignant brain tumors, presenting significant challenges for treatment due to their invasive nature and localization in critical brain regions. Standard treatment includes surgical resection followed by radiation and adjuvant chemothe...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Iman Karimi-Sani, Zahra Molavi, Samaneh Naderi, Seyedeh-Habibeh Mirmajidi, Iman Zare, Yasaman Naeimzadeh, Atena Mansouri, Amir Tajbakhsh, Amir Savardashtaki, Amirhossein Sahebkar
Format:	Article
Language:	English
Published:	BMC 2024-10-01
Subjects:	Personalized medicine mRNA vaccine Glioblastoma Clinical trials Brain cancer Brain tumor
Online Access:	https://doi.org/10.1186/s12951-024-02882-x