GRHL3 activates FSCN1 to relax cell-cell adhesions between migrating keratinocytes during wound reepithelialization

The migrating keratinocyte wound front is required for skin wound closure. Despite significant advances in wound healing research, we do not fully understand the molecular mechanisms that orchestrate collective keratinocyte migration. Here, we show that, in the wound front, the epidermal transcripti...

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Bibliographic Details

Published in:	JCI Insight
Main Authors:	Ghaidaa Kashgari, Sanan Venkatesh, Samuel Refuerzo, Brandon Pham, Anita Bayat, Rachel Herndon Klein, Raul Ramos, Albert Paul Ta, Maksim V. Plikus, Ping H. Wang, Bogi Andersen
Format:	Article
Language:	English
Published:	American Society for Clinical investigation 2021-09-01
Subjects:	Dermatology Genetics
Online Access:	https://doi.org/10.1172/jci.insight.142577