Development of a versatile [68Ga]Ga-FAPI-46 automated synthesis suitable to multi-elutions of germanium-68/gallium-68 generators

Gallium-68-labeled FAPI-46 has recently been proposed as a novel positron emission tomography imaging probe to diagnose and monitor a wide variety of cancers. Promising results from several ongoing clinical trials have led to a soaring demand for this radiotracer. Typical [68Ga]Ga-FAPI-46 labeling p...

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Bibliographic Details

Published in:	Frontiers in Chemistry
Main Authors:	Louis-Paul Paty, Simon Degueldre, Claire Provost, Camille Schmitt, Laura Trump, Julien Fouque, Charles Vriamont, Frank Valla, Thibault Gendron, Olivier Madar
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-07-01
Subjects:	PET FAPI radiopharmaceuticals radiosynthesis automation prepurification gallium-68
Online Access:	https://www.frontiersin.org/articles/10.3389/fchem.2024.1411312/full