Immunosuppressive tumor microenvironment and advance in immunotherapy in melanoma bone metastasis

Melanoma frequently develops bone metastases, leading to skeletal-related events and poor survival. The tumor microenvironment (TME) plays a pivotal role in melanoma progression, bone metastasis, and immunotherapy resistance. Key immunosuppressive cells including myeloid-derived suppressor cells (MD...

書誌詳細
出版年:	Frontiers in Immunology
主要な著者:	Yiqun Ma, Lin Zhang, Weimin Liu
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2025-08-01
主題:	melanoma bone metastasis osteoclasts tumor microenvironment immune checkpoint inhibitors immunotherapy
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1608215/full

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