Th17/1 and ex-Th17 cells are detected in patients with polyarticular juvenile arthritis and increase following treatment

Abstract Background A better understanding of the pathogenesis of polyarticular juvenile idiopathic arthritis (polyJIA) is needed to aide in the development of data-driven approaches to guide selection between therapeutic options. One inflammatory pathway of interest is JAK-STAT signaling. STAT3 is...

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Bibliographic Details

Published in:	Pediatric Rheumatology Online Journal
Main Authors:	Stephanie Wood, Justin Branch, Priscilla Vasquez, Marietta M. DeGuzman, Amanda Brown, Anna Carmela Sagcal-Gironella, Saimun Singla, Andrea Ramirez, Tiphanie P. Vogel
Format:	Article
Language:	English
Published:	BMC 2024-03-01
Subjects:	IL-6 STAT3 Th17 Treg Th17/1 Ex-Th17
Online Access:	https://doi.org/10.1186/s12969-024-00965-5