Aedes aegypti salivary gland extract alleviates acute itching by blocking TRPA1 channels

Aedes aegypti (Ae. aegypti) saliva induces a variety of anti-inflammatory and immunomodulatory activities. Interestingly, although it is known that mosquito bites cause allergic reactions in sensitised hosts, the primary exposure of humans to Ae. aegypti does not evoke significant itching. Whether a...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Anderson R. A. Cerqueira, Leandro Rodrigues, Silvia Abigail Coavoy-Sánchez, Simone A. Teixeira, Karla B. Feitosa, Erika Y. Taniguchi, Lucia R. Lopes, Antônio C. Cassola, Marcelo N. Muscará, Anderson Sá-Nunes, Soraia K. P. Costa
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Subjects:	nonhistaminergic skin itch sensory neurons TRPA1 salivary gland
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2023.1055706/full