Targeting CXCL1 chemokine signaling for treating cisplatin ototoxicity

Cisplatin is chemotherapy used for solid tumor treatment like lung, bladder, head and neck, ovarian and testicular cancers. However, cisplatin-induced ototoxicity limits the utility of this agent in cancer patients, especially when dose escalations are needed. Ototoxicity is associated with cochlear...

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Bibliographic Details
Published in:	Frontiers in Immunology
Main Authors:	Raheem F. H. Al Aameri, Entkhab M. A. Alanisi, Adu Oluwatosin, Dheyaa Al Sallami, Sandeep Sheth, Ian Alberts, Shree Patel, Leonard P. Rybak, Vickram Ramkumar
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	Cisplatin CXCL1 CXCR2 SB225002 Hair cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1125948/full

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