Awakening the dormant: Role of axonal guidance cues in stress-induced reorganization of the adult prefrontal cortex leading to depression-like behavior

Major depressive disorder (MDD) is a chronic and disabling disorder affecting roughly 280 million people worldwide. While multiple brain areas have been implicated, dysfunction of prefrontal cortex (PFC) circuitry has been consistently documented in MDD, as well as in animal models for stress-induce...

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Bibliographic Details

Published in:	Frontiers in Neural Circuits
Main Authors:	Ashraf Mahmud, Radu Gabriel Avramescu, Zhipeng Niu, Cecilia Flores
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	Netrin-1 social defeat post-mortem MDD ephrin slit
Online Access:	https://www.frontiersin.org/articles/10.3389/fncir.2023.1113023/full