Comparative Proteomic Analysis Reveals Mx1 Inhibits Senecavirus A Replication in PK-15 Cells by Interacting with the Capsid Proteins VP1, VP2 and VP3

As an emergent picornavirus pathogenic to pigs, Senecavirus A (SVA) can replicate in pig kidneys and proliferates well in porcine kidney epithelial PK-15 cells. Here, tandem mass tags (TMT) labeling coupled with liquid chromatography–tandem mass spectrometry (LC-MS/MS) was used to analyze the proteo...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Hang Gao, Zhaoying Xiang, Xinna Ge, Lei Zhou, Jun Han, Xin Guo, Yanhong Chen, Yongning Zhang, Hanchun Yang
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Subjects:	Senecavirus A (SVA) PK-15 cells tandem mass tags (TMT) liquid chromatography-tandem mass spectrometry (LC-MS/MS) differentially expressed proteins (DEPs) Mx1
Online Access:	https://www.mdpi.com/1999-4915/14/5/863