Moderate mechanical stress suppresses chondrocyte ferroptosis in osteoarthritis by regulating NF-κB p65/GPX4 signaling pathway

Abstract Ferroptosis is a recently identified form of programmed cell death that plays an important role in the pathophysiological process of osteoarthritis (OA). Herein, we investigated the protective effect of moderate mechanical stress on chondrocyte ferroptosis and further revealed the internal...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Scientific Reports
المؤلفون الرئيسيون: Juanjuan Han, Li-nan Zhan, Yue Huang, Shijia Guo, Xiaoding Zhou, Leonid Kapilevich, Zhuo Wang, Ke Ning, Mingli Sun, Xin-an Zhang
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Portfolio 2024-03-01
الموضوعات:
Mechanical stress
Osteoarthritis
Ferroptosis
Cartilage
الوصول للمادة أونلاين:https://doi.org/10.1038/s41598-024-55629-x

الانترنت

https://doi.org/10.1038/s41598-024-55629-x

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