A ROCK inhibitor suppresses the transforming growth factor-beta-2-induced endothelial–mesenchymal transition in Schlemm’s canal endothelial cells
Abstract In the normal eye, most of the aqueous humor drains through the trabecular meshwork (TM) and Schlemm’s canal (SC). The concentration of transforming growth factor beta 2 (TGF-β2) is increased in the aqueous humor of primary open angle glaucoma patients. TGF-β2 increases outflow resistance b...
| Published in: | Scientific Reports |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-06-01
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| Online Access: | https://doi.org/10.1038/s41598-023-36808-8 |