Evaluation of the Efficacy and Safety of the Fixed-Dose Combination of Nortriptyline-Pregabalin Versus Duloxetine-Pregabalin in the Treatment of Painful Diabetic Peripheral Neuropathy in a Tertiary Care Center in North India

Introduction: About 25% of patients with diabetes mellitus have painful diabetic peripheral neuropathy (PDPN). Chronic hyperglycemia causes neuronal death and nerve regeneration inhibition, causing diabetic neuropathy. It may severely impair touch, vibration, and lower-limb proprioception. Materials...

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Published in:	Journal of Diabetology
Main Authors:	Husain Abbas, Mujahid Beg, Hamid Ashraf, Syed Hasan Amir, Akash Priyadrashi
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2025-07-01
Subjects:	diabetes mellitus diabetic neuropathy dn-4 questionnaire duloxetine nortriptyline painful diabetic peripheral neuropathy pregabalin
Online Access:	https://doi.org/10.4103/jod.jod_20_25