Induction of regulatory T cells and efficacy of low-dose interleukin-2 in systemic sclerosis: interventional open-label phase 1–phase 2a study

Background Systemic sclerosis (SSc) is a chronic autoimmune disease, with impaired immune response, increased fibrosis and endothelial dysfunction. Regulatory T cells (Tregs), which are essential to control inflammation, tissue repair and autoimmunity, have a decreased frequency and impaired functio...

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Bibliographic Details

Published in:	RMD Open
Main Authors:	Michelle Rosenzwajg, Roberta Lorenzon, Patrice Cacoub, Arsène Mekinian, Anne Daguenel-Nguyen, Eric Vicaut, David Klatzmann, Sébastien Rivière, Olivier Fain, François Barde, Carlotta Cacciatore
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2024-05-01
Online Access:	https://rmdopen.bmj.com/content/10/2/e003500.full