HAPLN1 knockdown inhibits heart failure development via activating the PKA signaling pathway

Abstract Background Heart failure (HF) is a heterogeneous syndrome that affects millions worldwide, resulting in substantial health and economic burdens. However, the molecular mechanism of HF pathogenesis remains unclear. Methods HF-related key genes were screened by a bioinformatics approach.The i...

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Bibliographic Details
Published in:BMC Cardiovascular Disorders
Main Authors: Tao Yan, Shushuai Song, Wendong Sun, Yiping Ge
Format: Article
Language:English
Published: BMC 2024-04-01
Subjects:
Heart failure
HAPLN1
PKA signaling pathway
Online Access:https://doi.org/10.1186/s12872-024-03861-8

Internet

https://doi.org/10.1186/s12872-024-03861-8

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