Hemopexin promotes angiogenesis via up-regulating HO-1 in rats after cerebral ischemia-reperfusion injury

Abstract Background Ischemia-reperfusion (I/R) is a critical pathophysiological change of ischemic stroke. Heme-oxygenase-1 (HO-1) is a rate-limiting enzyme of eliminating excessive free heme by combining with hemopexin (HPX), a plasma protein contributing to alleviating infarct size due to ischemia...

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出版年:	BMC Anesthesiology
主要な著者:	Beibei Dong, Zhishen Zhang, Keliang Xie, Yongyan Yang, Yuan Shi, Chenxu Wang, Yonghao Yu
フォーマット:	論文
言語:	英語
出版事項:	BMC 2018-01-01
主題:	Cerebral ischemia Reperfusion injury Hemopexin Heme oxygenase Neovascularization
オンライン･アクセス:	http://link.springer.com/article/10.1186/s12871-017-0466-4