Hemopexin promotes angiogenesis via up-regulating HO-1 in rats after cerebral ischemia-reperfusion injury

Abstract Background Ischemia-reperfusion (I/R) is a critical pathophysiological change of ischemic stroke. Heme-oxygenase-1 (HO-1) is a rate-limiting enzyme of eliminating excessive free heme by combining with hemopexin (HPX), a plasma protein contributing to alleviating infarct size due to ischemia...

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Bibliographic Details
Published in:BMC Anesthesiology
Main Authors: Beibei Dong, Zhishen Zhang, Keliang Xie, Yongyan Yang, Yuan Shi, Chenxu Wang, Yonghao Yu
Format: Article
Language:English
Published: BMC 2018-01-01
Subjects:
Cerebral ischemia
Reperfusion injury
Hemopexin
Heme oxygenase
Neovascularization
Online Access:http://link.springer.com/article/10.1186/s12871-017-0466-4

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http://link.springer.com/article/10.1186/s12871-017-0466-4

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