Astragaloside IV ameliorate acute alcohol-induced liver injury in mice via modulating gut microbiota and regulating NLRP3/caspase-1 signaling pathway

Purpose Astragaloside IV (AS-IV) is a natural saponin substance extracted from the plant Radix Astragali with anti-inflammatory, antioxidant, anti-apoptotic, and liver-protecting effects. This study was to evaluate the liver protection effect of AS-IV on mice after acute alcohol stimulation.Material...

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Bibliographic Details

Published in:	Annals of Medicine
Main Authors:	Shan Wu, Fei Wen, Xiangbin Zhong, Wenjing Du, Manlian Chen, Junyi Wang
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2023-12-01
Subjects:	Alcoholic liver disease astragaloside IV hepatoprotective effect NLRP3 inflammasome gut microbiota
Online Access:	https://www.tandfonline.com/doi/10.1080/07853890.2023.2216942