A partitioned polygenic risk score reveals distinct contributions to psoriasis clinical phenotypes across a multi-ethnic cohort

Abstract Psoriasis is a chronic, immune-mediated inflammatory skin disease associated with a polygenic mode of inheritance. There are few studies that explore the association of a psoriasis Polygenic Risk Score (PRS) with patient clinical characteristics, and to our knowledge there are no studies ex...

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Bibliographic Details
Published in:Journal of Translational Medicine
Main Authors: Faye Orcales, Sugandh Kumar, Audrey Bui, Chandler Johnson, Jared Liu, Zhi-Ming Huang, Wilson Liao
Format: Article
Language:English
Published: BMC 2024-09-01
Online Access:https://doi.org/10.1186/s12967-024-05591-z