Novel—and Not So Novel—Inhibitors of the Multifunctional CRM1 Protein
Chromosome Region Maintenance 1 (CRM1), also known as Exportin 1 (XPO1), is a protein that is critical for transport of proteins and RNA to the cytoplasm through the nuclear pore complex. CRM1 inhibition with small molecule inhibitors is currently being studied in many cancers, including leukemias,...
| Published in: | Oncology Reviews |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-08-01
|
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/or.2024.1427497/full |