Novel—and Not So Novel—Inhibitors of the Multifunctional CRM1 Protein

Chromosome Region Maintenance 1 (CRM1), also known as Exportin 1 (XPO1), is a protein that is critical for transport of proteins and RNA to the cytoplasm through the nuclear pore complex. CRM1 inhibition with small molecule inhibitors is currently being studied in many cancers, including leukemias,...

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Bibliographic Details
Published in:	Oncology Reviews
Main Authors:	Waitman K. Aumann, Rafi Kazi, Amanda M. Harrington, Daniel S. Wechsler
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-08-01
Subjects:	CRM1 XPO1 cancer nuclear export leptomycin B
Online Access:	https://www.frontiersin.org/articles/10.3389/or.2024.1427497/full

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