High-throughput micro-CT analysis identifies sex-dependent biomarkers of erosive arthritis in TNF-Tg mice and differential response to anti-TNF therapy.

<h4>Background</h4>Development of reliable disease activity biomarkers is critical for diagnostics, prognostics, and novel drug development. Although computed tomography (CT) is the gold-standard for quantification of bone erosions, there are no consensus approaches or rationales for uti...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	H Mark Kenney, Kiana L Chen, Lindsay Schnur, Jeffrey I Fox, Ronald W Wood, Lianping Xing, Christopher T Ritchlin, Homaira Rahimi, Edward M Schwarz, Hani A Awad
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2024-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0305623