Phosphorylation of the MBF repressor Yox1p by the DNA replication checkpoint keeps the G1/S cell-cycle transcriptional program active.

<h4>Background</h4>In fission yeast Schizosaccharomyces pombe G1/S cell-cycle regulated transcription depends upon MBF. A negative feedback loop involving Nrm1p and Yox1p bound to MBF leads to transcriptional repression as cells exit G1 phase. However, activation of the DNA replication c...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Catia Caetano, Steffi Klier, Robertus A M de Bruin
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-02-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0017211&type=printable