Differential metabolomic pathway analysis in Malaysian childhood acute lymphoblastic leukemia patients treated with high-dose methotrexate

Background: Methotrexate (MTX) is the mainstay of the consolidation and maintenance phase of chemotherapy protocol for childhood acute lymphoblastic leukemia (ALL). This study aimed to investigate the altered metabolism associated with high dose-MTX and determine the potential of the metabolic marke...

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Bibliographic Details

Published in:	Pediatric Hematology Oncology Journal
Main Authors:	Rizal Husaini Razali, Lay Kek Teh, Mohd Zaki Salleh, Kok Hoi Teh, Hishamshah Mohd Ibrahim
Format:	Article
Language:	English
Published:	Elsevier 2024-09-01
Subjects:	Acute lymphoblastic leukemia Childhood Metabolic marker Methotrexate Metabolomics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2468124524000536