Molecular treatments to reduce catabolic effects in human meniscus explant models

Objectives: 1. To validate catabolic meniscus explant models induced by cytokines: interleukin-6 ​+ ​interleukin-6 receptor ​+ ​tumor necrosis factor alpha (IL6/TNF) and oncostatin M ​+ ​tumor necrosis factor alpha (OSM/TNF). 2. To evaluate three potential anti-catabolic treatments: i) dexamethasone...

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Bibliographic Details

Published in:	Osteoarthritis and Cartilage Open
Main Authors:	Amanda Sjögren, Karin Lindblom, Aleksandra Turkiewicz, Martin Englund, Patrik Önnerfjord
Format:	Article
Language:	English
Published:	Elsevier 2025-09-01
Subjects:	Meniscus Explant model Human tissue Proteomics Osteoarthritis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2665913125000548