P-glycoprotein: new insights into structure, physiological function, regulation and alterations in disease

The multidrug resistance phenomenon presents a major threat to the pharmaceutical industry. This resistance is a common occurrence in several diseases and is mediated by multidrug transporters that actively pump substances out of the cell and away from their target regions. The most well-known multi...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Iman Imtiyaz Ahmed Juvale, Azzmer Azzar Abdul Hamid, Khairul Bariyyah Abd Halim, Ahmad Tarmizi Che Has
Format:	Article
Language:	English
Published:	Elsevier 2022-06-01
Subjects:	P-glycoprotein Multidrug resistance Multidrug transporters Phospholipid bilayer Blood-brain barrier
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844022010659