Morphometric analysis of the thymic epithelial cell network using integrated and orthogonal digital pathology approaches

Abstract The thymus, a central organ for T cell development, lacks standardized pathology methods to assess its structure and function. Most studies rely on flow cytometry, which profiles thymic cell populations but offers limited spatial insight into tissue organization. This gap restricts our unde...

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Bibliographic Details

Published in:	Communications Biology
Main Authors:	Maria K. Lagou, Maria P. Markaki, Stepan Vodopyanov, Dimitrios G. Argyris, George K. Karagiorgis, Leslie Gunther-Cummins, Alexandros Hardas, Christos Panorias, Sophia DesMarais, Conner Entenberg, Randall S. Carpenter, Panagiota S. Filippou, Hillary Guzik, Xheni Nishku, Joseph Churaman, Vera DesMarais, Frank P. Macaluso, Maria Maryanovich, Katerina Angelopoulou, Theofilos Poutahidis, George S. Karagiannis
Format:	Article
Language:	English
Published:	Nature Portfolio 2026-04-01
Online Access:	https://doi.org/10.1038/s42003-026-10038-w