The APE2 Exonuclease Is a Client of the Hsp70–Hsp90 Axis in Yeast and Mammalian Cells

Molecular chaperones such as Hsp70 and Hsp90 help fold and activate proteins in important signal transduction pathways that include DNA damage response (DDR). Previous studies have suggested that the levels of the mammalian APE2 exonuclease, a protein critical for DNA repair, may be dependent on cha...

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发表在:	Biomolecules
Main Authors:	Siddhi Omkar, Tasaduq H. Wani, Bo Zheng, Megan M. Mitchem, Andrew W. Truman
格式:	文件
语言:	英语
出版:	MDPI AG 2022-06-01
主题:	Hsp70 Hsp90 APE2 Apn2 cancer chaperone inhibition
在线阅读:	https://www.mdpi.com/2218-273X/12/7/864