Multiple HPV integration mode in the cell lines based on long-reads sequencing

BackgroundThe integration of human papillomavirus (HPV) is closely related to the occurrence of cervical cancer. However, little is known about the complete state of HPV integration into the host genome.MethodsIn this study, three HPV-positive cell lines, HeLa, SiHa, and CaSki, were subjected to NAN...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Xiaofang Cui, Yiyan Li, Chuanpeng Zhang, Yanwei Qi, Yuhui Sun, Weiyang Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-12-01
Subjects:	HPV integration nanopore sequencing HPV16 HPV18 cervical cancer
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1294146/full