FCGR3A V158F gene polymorphism and trastuzumab response in HER2-positive breast cancer patients

Abstract Breast cancer is considered a multifactorial disease, with genetic factors playing an important role in diagnosis and treatment. FCGR3A encodes the receptor for the Fc portion of immunoglobulin G that has been linked to the trastuzumab response. Our study aimed to investigate the associatio...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Marwa A. Abdel-Wahed, Ghada Sadek Sabbour, Amira I. Hamed, Mohammed Sabry EL Kady, Shaimaa Khalil Mohammed, Menat Allah Ali Mahmoud Shaaban
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Subjects:
FCGR3A
Gene polymorphism
Trastuzumab
Online Access:https://doi.org/10.1038/s41598-024-76024-6

Internet

https://doi.org/10.1038/s41598-024-76024-6

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