Sirt6 regulates the proliferation of neural precursor cells and cortical neurogenesis in mice

Summary: Sirt6, a member of the class III histone deacetylases (HDACs), functions in the regulation of genomic stability, DNA repair, cancer, metabolism and aging. Sirt6 deficiency is lethal, and newborn SIRT6-null cynomolgus monkeys show unfinished brain development. After the generation of a corte...

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Bibliographic Details

Published in:	iScience
Main Authors:	Yufei Wei, Xinhuan Wang, Zhihua Ma, Pan Xiang, Gaoao Liu, Bin Yin, Lin Hou, Pengcheng Shu, Wei Liu, Xiaozhong Peng
Format:	Article
Language:	English
Published:	Elsevier 2024-02-01
Subjects:	Biological sciences developmental genetics developmental neuroscience
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004223027839