Ly6C<sup>hi</sup> Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation

Acute inflammation is a rapid and dynamic process involving the recruitment and activation of multiple cell types in a coordinated and precise manner. Here, we investigate the origin and transcriptional reprogramming of monocytes using a model of acute inflammation, zymosan-induced peritonitis. Mono...

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Bibliographic Details
Published in:Cells
Main Authors: Gareth S. D. Purvis, Eileen McNeill, Benjamin Wright, Keith M. Channon, David R. Greaves
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Subjects:
Ly6C<sup>hi</sup> monocytes
single cell transcriptomics
OxPhos
chemotaxis
Online Access:https://www.mdpi.com/2073-4409/13/11/916

Internet

https://www.mdpi.com/2073-4409/13/11/916

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