Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis

Abstract Background Nuclear respiratory factor 1 (NRF1) is a transcription factor that participates in several kinds of tumor, but its role in hepatocellular carcinoma (HCC) remains elusive. This study aims to explore the role of NRF1 in HCC progression and investigate the underlying mechanisms. Res...

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Bibliographic Details

Published in:	Biology Direct
Main Authors:	Ran Liu, Chuanzheng Yin, Peng Zhao, Bing Guo, Wenbo Ke, Xichuan Zheng, Dawei Xie, Yaofeng Wang, Gengqiao Wang, Yinzhao Jia, Yang Gao, Wenjun Hu, Gang Logan Liu, Zifang Song
Format:	Article
Language:	English
Published:	BMC 2023-10-01
Subjects:	NRF1 LPCAT1 Hepatocellular carcinoma Progression Positive feedback loop
Online Access:	https://doi.org/10.1186/s13062-023-00428-z