A composite subunit vaccine confers full protection against Buruli ulcer disease in the mouse footpad model of Mycobacterium ulcerans infection.

Buruli ulcer (BU) disease, a neglected necrotizing tropical skin infection caused by Mycobacterium ulcerans, is the third most common mycobacterial disease after tuberculosis and leprosy. Infections mostly occur in remote, rural areas of Central and West Africa, but also in Australia, Japan and Papu...

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Bibliographic Details

Published in:	PLoS Neglected Tropical Diseases
Main Authors:	Justice Kofi Boakye-Appiah, Andy C Tran, Matthew J Paul, Peter Hart, Richard O Phillips, Thomas S Harrison, Mark Wansbrough-Jones, Rajko Reljic
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-02-01
Online Access:	https://doi.org/10.1371/journal.pntd.0012710