Treating Cancer by Targeting Telomeres and Telomerase

Telomerase is expressed in more than 85% of cancer cells. Tumor cells with metastatic potential may have a high telomerase activity, allowing cells to escape from the inhibition of cell proliferation due to shortened telomeres. Human telomerase primarily consists of two main components: hTERT, a cat...

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出版年:	Antioxidants
主要な著者:	Marko Ivancich, Zachary Schrank, Luke Wojdyla, Brandon Leviskas, Adijan Kuckovic, Ankita Sanjali, Neelu Puri
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2017-02-01
主題:	telomerase DNA damage responses G-quadruplex guanine-rich oligonucleotides (GROs) telomere homolog oligonucleotides (T-oligos) shelterin complex
オンライン･アクセス:	http://www.mdpi.com/2076-3921/6/1/15