Neuropilin-1-target self-assembled peptide nanoparticles contribute to tumor treatment by inducing pyroptosis

Abstract Background Expression of the Neuropilin-1 (NRP1) is reported in malignant cells of multiple human tumor types represented as a tumor marker. Targeting NRP1 with a peptide, CK3, is used for tumor molecular imaging, raising the question of the therapeutic potential of CK2, a peptide with a CK...

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Bibliographic Details

Published in:	BMC Cancer
Main Authors:	Zheng Zhao, Jingyun Wang, Mengmeng Liu, Ziqian Li, Fei Cao, Pengfei Xu, Qi Fang, Jie Yang, Zhulong Hu, Di Wu, Rongbin Liu, Xuekui Liu
Format:	Article
Language:	English
Published:	BMC 2025-03-01
Subjects:	Neuropilin1 Cell-permeable peptides Anti-tumor Pyroptosis Immunotherapy
Online Access:	https://doi.org/10.1186/s12885-025-13784-y