CDK4-E2F3 signals enhance oxidative skeletal muscle fiber numbers and function to affect myogenesis and metabolism

Understanding how skeletal muscle fiber proportions are regulated is vital to understanding muscle function. Oxidative and glycolytic skeletal muscle fibers differ in their contractile ability, mitochondrial activity, and metabolic properties. Fiber-type proportions vary in normal physiology and dis...

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Bibliographic Details

Published in:	The Journal of Clinical Investigation
Main Authors:	Young Jae Bahn, Hariom Yadav, Paolo Piaggi, Brent S. Abel, Oksana Gavrilova, Danielle A. Springer, Ioannis Papazoglou, Patricia M. Zerfas, Monica C. Skarulis, Alexandra C. McPherron, Sushil G. Rane
Format:	Article
Language:	English
Published:	American Society for Clinical Investigation 2023-07-01
Subjects:	Metabolism Muscle biology
Online Access:	https://doi.org/10.1172/JCI162479