AMP‐dependent kinase stimulates the expression of αKlotho

Renal αKlotho along with fibroblast growth factor 23 regulates phosphate and vitamin D metabolism. Its cleavage yields soluble Klotho controlling intracellular processes. αKlotho has anti‐inflammatory and antioxidant effects and is nephro‐ and cardioprotective. AMP‐dependent kinase (AMPK) is a nephr...

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Bibliographic Details
Published in:FEBS Open Bio
Main Authors: Julia Vogt, Lisa Wolf, Ludwig E. Hoelzle, Martina Feger, Michael Föller
Format: Article
Language:English
Published: Wiley 2024-10-01
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13872