A viral-specific CD4+ T cell response protects female mice from Coxsackievirus B3 infection

BackgroundBiological sex plays an integral role in the immune response to various pathogens. The underlying basis for these sex differences is still not well defined. Here, we show that Coxsackievirus B3 (CVB3) induces a viral-specific CD4+ T cell response that can protect female mice from mortality...

Full description

Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Aryamav Pattnaik, Adeeba H. Dhalech, Stephanie A. Condotta, Caleb Corn, Martin J. Richer, Laura M. Snell, Christopher M. Robinson
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	Coxsackievirus B3 Enteric virus CD4 T cells T cells viral clearance sex differences
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1327384/full