Activin receptor-like kinase 7 promotes apoptosis of vascular smooth muscle cells via activating Smad2/3 signaling in diabetic atherosclerosis

Vascular smooth muscle cells (VSMCs) is a vital accelerator in the late phase of diabetic atherosclerosis, but the underlying mechanism remains unclear. The aim of our study was to investigate whether activin receptor-like kinase 7 (ALK7)-Smad2/3 pathway plays an important role in VSMC apoptosis of...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Shengchuan Cao, Qiuhuan Yuan, Qianqian Dong, Xilong Liu, Weikang Liu, Xiaoxuan Zhai, Chuanxin Zhang, Han Liu, Mengxiong Tang, Shujian Wei, Yuguo Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Subjects:	diabetic atherosclerosis activin receptor-like kinase 7 vascular smooth muscle cells apoptosis Smad2/3
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.926433/full