Caenorhabditis elegans PIEZO channel coordinates multiple reproductive tissues to govern ovulation

PIEZO1 and PIEZO2 are newly identified mechanosensitive ion channels that exhibit a preference for calcium in response to mechanical stimuli. In this study, we discovered the vital roles of pezo-1, the sole PIEZO ortholog in Caenorhabditiselegans, in regulating reproduction. A number of deletion all...

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Bibliographic Details

Published in:	eLife
Main Authors:	Xiaofei Bai, Jeff Bouffard, Avery Lord, Katherine Brugman, Paul W Sternberg, Erin J Cram, Andy Golden
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2020-06-01
Subjects:	PIEZO disease modeling calcium signaling ovulation spermatheca sperm navigation
Online Access:	https://elifesciences.org/articles/53603