Short- and long-term pathologic responses to quartz are induced by nearly free silanols formed during crystal fracturing

Abstract Background Inhalation of respirable crystalline silica particles, including quartz, is associated with an increased risk of developing pathologies, including persistent lung inflammation, fibrosis, cancer, and systemic autoimmunity. We demonstrated that the nearly free silanols (NFS) genera...

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Bibliographic Details

Published in:	Particle and Fibre Toxicology
Main Authors:	Cristina Pavan, Riccardo Leinardi, Anissa Benhida, Saloua Ibouraadaten, Yousof Yakoub, Sybille van den Brule, Dominique Lison, Francesco Turci, François Huaux
Format:	Article
Language:	English
Published:	BMC 2024-12-01
Subjects:	Quartz Silica Respirable crystalline silica Silanols Inflammation Fibrosis
Online Access:	https://doi.org/10.1186/s12989-024-00611-8