Zinc-limited Mycobacterium tuberculosis stimulate distinct responses in macrophages compared with standard zinc-replete bacteria

ABSTRACT Tuberculosis (TB) is notoriously difficult to treat, likely due to the complex host-pathogen interactions driven by pathogen heterogeneity. An understudied area of TB pathogenesis is host responses to Mycobacterium tuberculosis bacteria (Mtb) that are limited in zinc ions. This distinct pop...

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Bibliographic Details

Published in:	Infection and Immunity
Main Authors:	Endrei Marcantonio, Allexa D. Burger, Kelly H. Chang, Fukun W. Hoffmann, Yuanyuan Fu, Vedbar S. Khadka, Benoit J. Smagghe, Youping Deng, Peter R. Hoffmann, Sladjana Prisic
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-03-01
Subjects:	Mycobacterium tuberculosis macrophages zinc
Online Access:	https://journals.asm.org/doi/10.1128/iai.00578-24