A mathematical model for the dependence of keratin aggregate formation on the quantity of mutant keratin expressed in EGFP-K14 R125P keratinocytes.

We examined keratin aggregate formation and the possible mechanisms involved. With this aim, we observed the effect that different ratios between mutant and wild-type keratins expressed in cultured keratinocytes may have on aggregate formation in vitro, as well as how keratin aggregate formation aff...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Marcos Gouveia, Tjaša Sorčan, Špela Zemljič-Jokhadar, Rui D M Travasso, Mirjana Liović
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261227&type=printable