In Vitro Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Amphotericin B against <i>Candida auris</i>

The aims of this study were to characterize the antifungal activity of amphotericin B against <i>Candida auris</i> in a static in vitro system and to evaluate different dosing schedules and MIC scenarios by means of semi-mechanistic pharmacokinetic/pharmacodynamic (PK/PD) modelling and s...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Unai Caballero, Elena Eraso, Javier Pemán, Guillermo Quindós, Valvanera Vozmediano, Stephan Schmidt, Nerea Jauregizar
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Subjects:	<i>Candida auris</i> PK/PD model amphotericin B time-kill curves
Online Access:	https://www.mdpi.com/1999-4923/13/11/1767