Small extracellular vesicles derived from dermal fibroblasts promote fibroblast activity and skin development through carrying miR-218 and ITGBL1

Abstract Skin thickness is closely related to the appearance of human skin, such as sagging and wrinkling, which primarily depends on the level of collagen I synthesized by dermal fibroblasts (DFs). Small extracellular vesicles (SEVs), especially those derived from human DFs (HDFs), are crucial orch...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Qin Zou, Mei Zhang, Rong Yuan, Yifei Wang, Zhengyin Gong, Rui Shi, Yujing Li, Kaixin Fei, Chenggang Luo, Ying Xiong, Ting Zheng, Li Zhu, Guoqing Tang, Mingzhou Li, Xuewei Li, Yanzhi Jiang
Format:	Article
Language:	English
Published:	BMC 2022-06-01
Subjects:	Dermal fibroblasts Small extracellular vesicles Fibroblast activity Skin development miR-218 ITGBL1
Online Access:	https://doi.org/10.1186/s12951-022-01499-2