Reduction in mitochondrial iron alleviates cardiac damage during injury

Abstract Excess cellular iron increases reactive oxygen species (ROS) production and causes cellular damage. Mitochondria are the major site of iron metabolism and ROS production; however, few studies have investigated the role of mitochondrial iron in the development of cardiac disorders, such as i...

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Bibliographic Details

Published in:	EMBO Molecular Medicine
Main Authors:	Hsiang‐Chun Chang, Rongxue Wu, Meng Shang, Tatsuya Sato, Chunlei Chen, Jason S Shapiro, Ting Liu, Anita Thakur, Konrad T Sawicki, Sathyamangla VN Prasad, Hossein Ardehali
Format:	Article
Language:	English
Published:	Springer Nature 2016-02-01
Subjects:	heart failure iron ischemia ischemia/reperfusion mitochondria
Online Access:	https://doi.org/10.15252/emmm.201505748