Overexpression of miRNA-216 in exosomes derived from umbilical cord mesenchymal stem cells promotes angiogenesis and improves functional recovery after spinal cord injury

Objective(s): This study aimed to engineer miR-216-overexpressing umbilical cord mesenchymal stem cells (UCMSCs) to generate miR-216-enriched UCMSC-derived exosomes (UCMSC-Exos) and evaluate their therapeutic potential in Spinal cord injury (SCI).Materials and Methods: miR-216 overexpression was ach...

Full description

Bibliographic Details

Published in:	Iranian Journal of Basic Medical Sciences
Main Authors:	Hengde Li, Renfeng Yi, Youbing Fan, Gonghao Zhan, Taoyuan Xiao
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2025-10-01
Subjects:	angiogenesis exosomes mirna-216 spinal cord injury umbilical cord-mesenchymal stem cells
Online Access:	https://ijbms.mums.ac.ir/article_26182_5cfaf562e1d0f81826d7073a626aa3e4.pdf