The advance on pathophysiological mechanisms of type 2 chronic rhinosinusitis with nasal polyposis

PurposeThis review aims to explore the pathophysiological mechanisms and emerging therapies for type 2 chronic rhinosinusitis with nasal polyps (CRSwNP), driven primarily by type 2 inflammation.Search methodsA comprehensive search of relevant literature was performed in databases including PubMed, W...

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Bibliographic Details

Published in:	Frontiers in Allergy
Main Authors:	Cheng Yang, Ling Guo, Yuhan Wang, Wenjing Jiang, Sijia Chen, Qingjia Gu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Subjects:	chronic rhinosinusitis with nasal polyposis (CRSwNP) type 2 T helper cells (Th2) type 2 innate lymphoid cells (ILC2s) epithelial barrier dysfunction biologics
Online Access:	https://www.frontiersin.org/articles/10.3389/falgy.2025.1599797/full