Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs

Nicotinic acetylcholine receptors (nAChRs) are targets for developing new drugs to treat severe pain, nicotine addiction, Alzheimer disease, epilepsy, etc. α-Conotoxins are biologically and chemically diverse. With 12–19 residues and two disulfides, they can be specifically selected for different nA...

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Bibliographic Details

Published in:	Marine Drugs
Main Authors:	Bo Lin, Shihua Xiang, Mengsen Li
Format:	Article
Language:	English
Published:	MDPI AG 2016-10-01
Subjects:	α-conotoxins nAChRs Ac-AChBP X-ray structure model design
Online Access:	http://www.mdpi.com/1660-3397/14/10/173