Hepatic bile acids and bile acid-related gene expression in pregnant and lactating rats

Background. Significant physiological changes occur during pregnancy and lactation. Intrahepatic cholestasis of pregnancy (ICP) is a liver disease closely related to disruption of bile acid homeostasis. The objective of this study was to examine the regulation of bile acid synthesis and transport in...

Full description

Bibliographic Details

Published in:	PeerJ
Main Authors:	Qiong N. Zhu, Hong M. Xie, Dan Zhang, Jie Liu, Yuan F. Lu
Format:	Article
Language:	English
Published:	PeerJ Inc. 2013-08-01
Subjects:	Liver bile acids FXR-SHP Ntcp and Bsep Cyp7a1 Pregnant and lactating rats Oatps
Online Access:	https://peerj.com/articles/143.pdf