R-spondin 3 governs secretory differentiation in the gastric oxyntic glands

The gastric oxyntic glands are maintained by gastric stem cells that continuously supply all differentiated cell types within the corpus epithelium. Stem cells are supported by stromal cells that make up the stem cell niche. In this issue of the JCI, Fischer et al. report on their use of genetically...

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Bibliographic Details
Published in:The Journal of Clinical Investigation
Main Authors: Ken Kurokawa, Timothy C. Wang, Yoku Hayakawa
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022-11-01
Online Access:https://doi.org/10.1172/JCI163380